INT108103

Context Info Confidence 0.05 First Reported 2003 Last Reported 2003 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.12 Pain Relevance 0

cytosol (Nos2) signal transduction (Nos2) extracellular space (Nos2) oxidoreductase activity (Nos2) peroxisome (Nos2) nucleus (Nos2)

Anatomy Link Frequency liver 2 Mir1893 (Mus musculus) Nos2 (Mus musculus)

Pain Link Frequency Relevance Heat Glutamate receptor 2 50.00 Paracetamol 1 50.00 antagonist 2 5.00

Disease Link Frequency Relevance Heat Stress 1 62.56 Hepatotoxicity 2 61.44 Hypoxia 1 5.00 Death 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

MPEP, SIB-1893 and SIB-1757 (all at 20 mg/kg, i.p.) also reduced the increased expression and activity of liver iNOS induced by acetaminophen.

SIB-1893 Negative_regulation (reduced) of Gene_expression (expression) of iNOS in liver

1) Confidence 0.05 Published 2003 Journal J. Hepatol. Section Body Doc Link 12547406 Disease Relevance 0.12 Pain Relevance 0

General Comments

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