INT109464

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Context Info
Confidence 0.04
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Dmp1, Tyr) extracellular matrix organization (Dmp1) pigmentation (Tyr)
cell proliferation (Tyr) extracellular region (Dmp1) oxidoreductase activity (Tyr)
Dmp1 (Mus musculus)
Tyr (Mus musculus)
Pain Link Frequency Relevance Heat
mu opioid receptor 2 98.42 Very High Very High Very High
Analgesic 1 30.32 Quite Low
Morphine 1 26.80 Quite Low
Opioid 1 25.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To investigate the value of the 2',6'-dimethylphenylalanine (Dmp) residue as an aromatic amino acid substitution, we prepared analogues of the mu opioid receptor-selective dermorphin tetrapeptide Tyr-D-Arg-Phe-betaAla-NH(2) (YRFB) in which Dmp or its D-isomer replaced Tyr(1) or Phe(3).
Dmp Negative_regulation (replaced) of Tyr associated with mu opioid receptor
1) Confidence 0.04 Published 2003 Journal Bioorg. Med. Chem. Lett. Section Abstract Doc Link 12657261 Disease Relevance 0 Pain Relevance 0.09

General Comments

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