INT109718

Context Info Confidence 0.25 First Reported 2003 Last Reported 2003 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.81 Pain Relevance 0.67

extracellular space (Tac1, Mpo) mitochondrion (Mpo) oxidoreductase activity (Mpo) extracellular region (Tac1) plasma membrane (Tac1) lysosome (Mpo)

Tac1 (Mus musculus) Mpo (Mus musculus)

Pain Link Frequency Relevance Heat Calcitonin gene-related peptide 3 100.00 antagonist 1 100.00 qutenza 2 99.90 Inflammation 11 92.96

Disease Link Frequency Relevance Heat Urological Neuroanatomy 3 100.00 INFLAMMATION 7 92.96 Mucositis 1 86.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

NO synthase inhibitors, L-NAME and aminoguanidine, as well as the neurotoxin capsaicin and NK1, calcitonin gene-related peptide (CGRP) receptor antagonists, SR140333 and CGRP(8-37), prevented SLIGRL-induced MPO and damage score increases and permeability.

NK1 Negative_regulation (prevented) of MPO associated with qutenza, antagonist, urological neuroanatomy and calcitonin gene-related peptide

1) Confidence 0.25 Published 2003 Journal J. Immunol. Section Abstract Doc Link 12682265 Disease Relevance 0.81 Pain Relevance 0.67

General Comments

This test has worked.