INT112386

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Context Info
Confidence 0.47
First Reported 2003
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.72
Pain Relevance 0.77

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (IL1RL1) extracellular space (IL1RL1) extracellular region (IL1RL1)
plasma membrane (IL1RL1) intracellular (IL1RL1)
Anatomy Link Frequency
central area 2
IL1RL1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 2 100.00 Very High Very High Very High
antagonist 1 100.00 Very High Very High Very High
rheumatoid arthritis 5 97.04 Very High Very High Very High
imagery 19 88.88 High High
Inflammation 3 88.16 High High
Migraine 3 65.24 Quite High
depression 11 50.00 Quite Low
Action potential 5 5.00 Very Low Very Low Very Low
medulla 4 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 7 100.00 Very High Very High Very High
INFLAMMATION 5 100.00 Very High Very High Very High
Disease 4 100.00 Very High Very High Very High
Necrosis 1 100.00 Very High Very High Very High
Rheumatoid Arthritis 5 97.04 Very High Very High Very High
Foreign Bodies 49 93.60 High High
Soft Tissue Neoplasm 4 92.80 High High
Cognitive Disorder 3 88.60 High High
Hematoma 4 77.44 Quite High
Foreign-body Granuloma 16 68.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The current therapeutic model encourages a step-up approach that safely incorporates several currently available classes of agents: non-steroidal anti-inflammatory drugs, selective cyclo-oxygenase-2 inhibitors, glucocorticoids, disease-modifying anti-rheumatic drugs, and biological agents (tumour necrosis factor-alpha inhibitors and interleukin-1 receptor antagonist).
Positive_regulation (incorporates) of Gene_expression (antagonist) of interleukin-1 receptor associated with necrosis, inflammation, cancer, antagonist, cinod and disease
1) Confidence 0.47 Published 2003 Journal Best Pract Res Clin Rheumatol Section Abstract Doc Link 12915159 Disease Relevance 1.19 Pain Relevance 0.51
The twitches, be it T1 or T4, were calculated identically using the calculated peak value of [ARA] after the first or the fourth stimulus:
Positive_regulation (calculated) of Gene_expression (be) of T1
2) Confidence 0.25 Published 2007 Journal Theor Biol Med Model Section Body Doc Link PMC1939837 Disease Relevance 0 Pain Relevance 0
The central area of the reactive lesion is observed as low intensities on T1- and high intensities on T2-weighted images with no enhancement, which suggests that the lesion is myxomatous or cystic (8,9).
Positive_regulation (intensities) of Gene_expression (intensities) of T1 in central area
3) Confidence 0.24 Published 2009 Journal Upsala Journal of Medical Sciences Section Body Doc Link PMC2852748 Disease Relevance 1.16 Pain Relevance 0.20
There are differences between the data presented in this paper and that obtained by SS stimulation:
Positive_regulation (by) of Gene_expression (obtained) of stimulation
4) Confidence 0.03 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1483834 Disease Relevance 0.37 Pain Relevance 0.07

General Comments

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