INT113364

Context Info Confidence 0.44 First Reported 2003 Last Reported 2010 Negated 1 Speculated 0 Reported most in Body Documents 2 Total Number 4 Disease Relevance 1.90 Pain Relevance 0.41

transferase activity, transferring acyl groups (NAA50) cytoplasm (NAA50)

NAA50 (Homo sapiens)

Pain Link Frequency Relevance Heat headache 1 94.36 Dismenorea 1 92.96 fibrosis 6 78.28 Action potential 87 78.24 metalloproteinase 12 43.12 action potential duration 6 5.00 Nav1.1 3 5.00

Disease Link Frequency Relevance Heat Aging 33 99.68 Hypertrophy 18 96.84 Headache 1 94.36 Dizziness 2 93.96 Reprotox - General 1 3 92.96 Pallor 1 85.20 Anaemia 4 84.28 Fibrosis 15 78.28 Heart Rate Under Development 27 77.20 Myoma 4 75.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

While side effects were encountered in 80.0% of patients in the oral iron group, no significant side effects were observed in the Toki-shakuyaku-san group.

Neg (no) Regulation (effects) of san

1) Confidence 0.44 Published 2003 Journal Yakugaku Zasshi Section Abstract Doc Link 14513774 Disease Relevance 1.15 Pain Relevance 0.19

The aim of this study was to study the changes in the structure and function of the SAN during ageing.

Regulation (changes) of SAN associated with aging

2) Confidence 0.17 Published 2010 Journal Journal of Molecular and Cellular Cardiology Section Body Doc Link PMC2845824 Disease Relevance 0.17 Pain Relevance 0.12

Alings et al. [8] used Picro Sirius red to measure collagen protein and they reported that in the human SAN, from adulthood, there is no age-dependent increase in collagen protein and there is also no age-dependent change in the cat SAN.

Regulation (change) of SAN

3) Confidence 0.08 Published 2010 Journal Journal of Molecular and Cellular Cardiology Section Body Doc Link PMC2845824 Disease Relevance 0.22 Pain Relevance 0

Age-dependent change in SAN function

Regulation (change) of SAN

4) Confidence 0.08 Published 2010 Journal Journal of Molecular and Cellular Cardiology Section Body Doc Link PMC2845824 Disease Relevance 0.36 Pain Relevance 0.10

General Comments

This test has worked.