INT113573

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Context Info
Confidence 0.04
First Reported 2003
Last Reported 2003
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (DMRT1) nucleus (DMRT1)
DMRT1 (Homo sapiens)
FAIM3 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 2 94.24 High High
Opioid 1 92.32 High High
Kappa opioid receptor 2 89.92 High High
opioid receptor 1 83.00 Quite High
Spinal cord 1 80.20 Quite High
mu opioid receptor 2 72.84 Quite High
Enkephalin 1 60.00 Quite High
intrathecal 1 50.68 Quite High
Analgesic 1 49.48 Quite Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
All Dmt1 analogs showed much higher affinity for the mu receptor than corresponding Tyr1 analogs. [35S]GTPgammaS (guanosine 5'-O -(3-[35S]thio)triphosphate) binding showed that [Dmt1]DALDA and DAMGO are full agonists at hMOR and hDOR but are only partial agonists at hKOR.
Dmt1 Spec (partial) Binding (affinity) of mu receptor associated with agonist
1) Confidence 0.04 Published 2003 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 14534366 Disease Relevance 0 Pain Relevance 0.47

General Comments

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