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Context Info
Confidence 0.67
First Reported 2003
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 1.45
Pain Relevance 0.66

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (REG1B) extracellular region (REG1B)
Anatomy Link Frequency
pancreas 1
stomach 1
REG1B (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 12 95.84 Very High Very High Very High
anesthesia 1 93.20 High High
methotrexate 1 82.40 Quite High
cINOD 2 76.96 Quite High
Crohn's disease 1 40.48 Quite Low
Neuropeptide 2 25.00 Low Low
Chronic pancreatitis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatitis 2 98.56 Very High Very High Very High
Stress 1 94.32 High High
Cancer 51 92.48 High High
Pancreatic Cancer 32 81.72 Quite High
Injury 10 77.56 Quite High
INFLAMMATION 2 76.76 Quite High
Sepsis 1 75.00 Quite High
Metastasis 4 65.20 Quite High
Stomach Cancer 2 60.32 Quite High
Congenital Anomalies 4 53.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A time course analysis of RegI expression during the onset and offset of adaptation showed that mucosal RegI increased during the development of adaptation, was maintained during subsequent aspirin dosing, and returned to baseline levels once dosing had ceased and adaptation was lost-indicative of a causal role in the adaptation process.
Gene_expression (expression) of RegI associated with aspirin
1) Confidence 0.67 Published 2003 Journal Lab. Invest. Section Abstract Doc Link 14563943 Disease Relevance 0.29 Pain Relevance 0.28
TFF gene and protein expression levels were similar in all three groups, whereas RegI gene expression and protein levels in adapted stomach were increased.
Gene_expression (expression) of RegI in stomach
2) Confidence 0.67 Published 2003 Journal Lab. Invest. Section Abstract Doc Link 14563943 Disease Relevance 0.30 Pain Relevance 0.25
Contrary to reg1A, reg1B, reg3A and reg3G genes, all located on chromosome 2p12, reg4 is on chromosome 1p13.1-p12.
Gene_expression (is) of reg1B
3) Confidence 0.53 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2760775 Disease Relevance 0.59 Pain Relevance 0.04
OBJECTIVES: The level of pancreatic stone protein/regenerating protein (PSP/reg), a secretory protein produced in the pancreas, increases dramatically during pancreatic disease.
Gene_expression (produced) of pancreatic stone protein in pancreas associated with pancreatitis
4) Confidence 0.28 Published 2009 Journal Crit. Care Med. Section Abstract Doc Link 19325491 Disease Relevance 0.27 Pain Relevance 0.09

General Comments

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