INT113978

Context Info Confidence 0.24 First Reported 2004 Last Reported 2004 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 1.20 Pain Relevance 0.51

pigmentation (MC1R) plasma membrane (MC1R) signal transducer activity (MC1R)

MC1R (Homo sapiens)

Pain Link Frequency Relevance Heat melanocortin 1 receptor 5 100.00 cytokine 3 83.12

Disease Link Frequency Relevance Heat Lung Cancer 9 91.68 Malignant Neoplastic Disease 3 90.24 Pleural Effusion 1 89.16 Cancer 3 85.76

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Immunoneutralization of MC1R in the cell lines enhanced expression of interleukin-8 (IL-8), IL-6, and transforming growth factor-beta.

Positive_regulation (enhanced) of Localization (Immunoneutralization) of MC1R associated with melanocortin 1 receptor

1) Confidence 0.24 Published 2004 Journal J. Leukoc. Biol. Section Abstract Doc Link 14576363 Disease Relevance 1.20 Pain Relevance 0.51

General Comments

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