INT114449

Context Info Confidence 0.00 First Reported 2003 Last Reported 2003 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.34 Pain Relevance 0.13

cell differentiation (Camk1) signal transduction (Camk1) nucleocytoplasmic transport (Camk1) nucleus (Camk1) cell cycle (Camk1) cytoplasm (Camk1)

Camk1 (Rattus norvegicus)

Pain Link Frequency Relevance Heat nMDA receptor 2 75.00 cerebral cortex 1 75.00 tetrodotoxin 1 51.76

Disease Link Frequency Relevance Heat Convulsion 5 99.76

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Following seizure induction, CaMKII-alpha expression was downregulated and CaMKII-delta expression upregulated while CaMKII-beta and CaMKII-gamma expression was unaffected.

Negative_regulation (downregulated) of Gene_expression (expression) of CaMKII-alpha associated with convulsion

1) Confidence 0.00 Published 2003 Journal Neuroscience Section Abstract Doc Link 14614906 Disease Relevance 0.34 Pain Relevance 0.13

General Comments

This test has worked.