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Context Info
Confidence 0.01
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.72
Pain Relevance 0.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Hmmr, Casp3) cytosol (Casp3) peptidase activity (Casp3)
mitochondrion (Casp3) nucleus (Casp3) intracellular (Casp3)
Anatomy Link Frequency
liver 2
Hmmr (Mus musculus)
Casp3 (Mus musculus)
Pain Link Frequency Relevance Heat
qutenza 2 99.78 Very High Very High Very High
primary afferent fibers 2 99.34 Very High Very High Very High
antagonist 5 92.28 High High
substance P 6 91.04 High High
cytokine 2 88.08 High High
Disease Link Frequency Relevance Heat
Hepatotoxicity 4 93.96 High High
Apoptosis 5 93.24 High High
Injury 2 76.64 Quite High
Cancer 2 75.00 Quite High
Necrosis 2 75.00 Quite High
Disease 1 75.00 Quite High
Liver Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Depletion of primary afferent nerve fibers by neonatal capsaicin treatment prevented CD95-mediated activation of caspase-3, measured as enzymatic activity in liver homogenates or by demonstration of hepatocellular immunoreactivity for active caspase-3 in liver slices, and liver damage.
Negative_regulation (prevented) of CD95-mediated Positive_regulation (activation) of caspase-3 in liver associated with qutenza, primary afferent fibers and hepatotoxicity
1) Confidence 0.01 Published 2004 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 14617692 Disease Relevance 0.72 Pain Relevance 0.60

General Comments

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