INT114754

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Context Info
Confidence 0.08
First Reported 2004
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.67
Pain Relevance 0.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il6, Crp) extracellular region (Il6, Crp) aging (Il6)
Anatomy Link Frequency
smooth muscle cell 2
Il6 (Rattus norvegicus)
Crp (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Analgesic 2 93.36 High High
Perioperative pain 1 92.80 High High
Inflammation 13 91.60 High High
cINOD 1 91.04 High High
cytokine 2 37.28 Quite Low
Angina 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Percutaneous transluminal coronary angioplasty 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 10 96.08 Very High Very High Very High
Pneumonia 51 95.96 Very High Very High Very High
Post Operative Pain 1 92.80 High High
INFLAMMATION 14 91.60 High High
Hyperplasia 17 84.16 Quite High
Acute-phase Reaction 2 75.00 Quite High
Chlamydia Infection 7 50.00 Quite Low
Pressure Volume 2 Under Development 1 25.00 Low Low
Postoperative Complications 1 25.00 Low Low
Shock 3 22.56 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, preoperative administration of ibuprofen has proved to reduce interleukin-6 (IL-6) release, while that of ranitidine reduced postoperative IL-6-induced C-reactive protein synthesis in patients undergoing abdominal surgery.
IL-6-induced Positive_regulation (induced) of Gene_expression (synthesis) of C-reactive protein
1) Confidence 0.08 Published 2004 Journal Eur Spine J Section Abstract Doc Link 14634855 Disease Relevance 0.41 Pain Relevance 0.36
In vivo, IL-6 is a strong inducer of liver C-reactive protein (CRP) production which is able to stimulate endothelial and smooth muscle cell proliferation providing a pathway for Cpn to aggravate vein graft failure [24].
IL-6 Positive_regulation (inducer) of Gene_expression (production) of C-reactive protein in smooth muscle cell associated with pneumonia
2) Confidence 0.02 Published 2007 Journal BMC Microbiol Section Body Doc Link PMC2222630 Disease Relevance 1.26 Pain Relevance 0.11

General Comments

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