INT115348

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Context Info
Confidence 0.68
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 5
Disease Relevance 1.76
Pain Relevance 2.99

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Baiap2) signal transduction (Baiap2) nucleolus (Baiap2)
plasma membrane (Baiap2) nucleus (Baiap2) cytoplasm (Baiap2)
Anatomy Link Frequency
thoracic 3
CNAN 1
dorsal 1
Baiap2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
substance P 10 100.00 Very High Very High Very High
Spinal cord 25 99.24 Very High Very High Very High
dorsal rhizotomy 5 98.76 Very High Very High Very High
bradykinin 5 93.80 High High
adenocard 5 93.32 High High
algogenic 5 91.64 High High
Inflammation 5 89.52 High High
Angina 10 77.76 Quite High
ischemia 5 75.00 Quite High
nociceptor 5 25.00 Low Low
Disease Link Frequency Relevance Heat
Nociception 10 97.48 Very High Very High Very High
INFLAMMATION 5 89.52 High High
Cv General 3 Under Development 10 77.76 Quite High
Coronary Artery Disease 5 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This CoAO-induced irSP release was eliminated after thoracic dorsal rhizotomy.
Localization (release) of irSP in dorsal associated with dorsal rhizotomy
1) Confidence 0.68 Published 2004 Journal Am. J. Physiol. Heart Circ. Physiol. Section Abstract Doc Link 14684370 Disease Relevance 0.38 Pain Relevance 0.68
Antibody-coated microprobes were inserted into the thoracic (T3-4) spinal cord in urethane-anesthetized Sprague-Dawley rats to detect the differences in the release of immunoreactive substance P-like (irSP) substances in response to differential activation of cardiac nociceptive sensory neurons (CNAN).
Localization (release) of irSP in thoracic associated with nociception, substance p and spinal cord
2) Confidence 0.68 Published 2004 Journal Am. J. Physiol. Heart Circ. Physiol. Section Abstract Doc Link 14684370 Disease Relevance 0.26 Pain Relevance 0.45
Conversely, CoAO augmented the release of irSP from T3-4 spinal segments from laminae I-VII.
Localization (release) of irSP in T3-4
3) Confidence 0.59 Published 2004 Journal Am. J. Physiol. Heart Circ. Physiol. Section Abstract Doc Link 14684370 Disease Relevance 0.38 Pain Relevance 0.67
Stimulation of the CNAN by IES did not alter the pattern of release of irSP.
Localization (release) of irSP in CNAN
4) Confidence 0.59 Published 2004 Journal Am. J. Physiol. Heart Circ. Physiol. Section Abstract Doc Link 14684370 Disease Relevance 0.37 Pain Relevance 0.62
There was widespread basal release of irSP from the thoracic spinal cord.
Localization (release) of irSP in thoracic associated with spinal cord
5) Confidence 0.59 Published 2004 Journal Am. J. Physiol. Heart Circ. Physiol. Section Abstract Doc Link 14684370 Disease Relevance 0.37 Pain Relevance 0.57

General Comments

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