INT115999

Context Info Confidence 0.25 First Reported 2004 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 3 Total Number 4 Disease Relevance 1.83 Pain Relevance 0.09

signal transduction (PTPLA) lyase activity (PTPLA) endoplasmic reticulum (PTPLA)

PTPLA (Homo sapiens)

Pain Link Frequency Relevance Heat Pain 19 92.48 Sciatica 4 50.00 depression 4 5.00 addiction 2 5.00 headache 2 5.00 alcohol 2 5.00

Disease Link Frequency Relevance Heat Skin Infection 10 99.84 Autoimmune Disease 1 99.26 Bullous Skin Disease 1 98.78 Adhesions 1 91.00 Sprains And Strains 1 88.96 Disease 33 84.36 Abscess 1 80.88 Staphylococcus Infection 1 80.32 Streptococcus Infection 2 79.84 Ecthyma 1 79.44

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

However, the HCA is associated with difficulties which in turn affect the CAP.

Regulation (affect) of CAP

1) Confidence 0.25 Published 2008 Journal Cost Eff Resour Alloc Section Body Doc Link PMC2553058 Disease Relevance 0 Pain Relevance 0

Further work, including examination of the frequency and force duration dependency of SMT, is necessary to elucidate the clinical relevance of enhanced or absent CAP responses in patients.

Regulation (responses) of CAP

2) Confidence 0.20 Published 2004 Journal J Manipulative Physiol Ther Section Body Doc Link 14739869 Disease Relevance 0 Pain Relevance 0

This section illustrates these issues and critically discusses how CAP can be affected by employing diverse approaches.

Regulation (affected) of CAP

3) Confidence 0.11 Published 2008 Journal Cost Eff Resour Alloc Section Body Doc Link PMC2553058 Disease Relevance 0 Pain Relevance 0

Recent experiments have revealed similarities in the pathophysiology of SSSS and pemphigus foliaceus, an autoimmune disorder that is characterized by antibodies targeting the same epidermal attachment protein.

Regulation (targeting) of attachment protein associated with skin infection, autoimmune disease and bullous skin disease

4) Confidence 0.07 Published 2004 Journal Expert Rev Anti Infect Ther Section Abstract Doc Link 15482221 Disease Relevance 1.83 Pain Relevance 0.09

General Comments

This test has worked.