INT116644

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Context Info
Confidence 0.61
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 0.68
Pain Relevance 0.78

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

carbohydrate metabolic process (Gsk3b) protein complex (Gsk3b) response to stress (Gsk3b)
cytoplasm (Gsk3b) cytosol (Gsk3b) nucleolus (Gsk3b)
Gsk3b (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Opioid 9 75.00 Quite High
ischemia 9 72.20 Quite High
Bile 61 61.52 Quite High
MU agonist 6 50.96 Quite High
Morphine 3 48.84 Quite Low
agonist 3 46.76 Quite Low
dexamethasone 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 9 72.20 Quite High
Fistula 19 61.12 Quite High
Repression 4 5.00 Very Low Very Low Very Low
Bordatella Infection 3 5.00 Very Low Very Low Very Low
Van Bogaert's Disease 3 5.00 Very Low Very Low Very Low
Toxicity 1 5.00 Very Low Very Low Very Low
Vesicular Stomatitis 1 5.00 Very Low Very Low Very Low
Biliary Fistula 1 5.00 Very Low Very Low Very Low
Cytomegalovirus Infection 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data indicate that OIC occurs via the phosphorylation of GSKbeta at Ser9 during reperfusion.
Phosphorylation (phosphorylation) of GSKbeta
1) Confidence 0.61 Published 2004 Journal Circ. Res. Section Abstract Doc Link 14976126 Disease Relevance 0.18 Pain Relevance 0.22
Furthermore, no differences were seen in phosphorylation of GSKalpha (Ser21 or Tyr279) or phosphorylation of GSKbeta (Tyr216).
Phosphorylation (phosphorylation) of GSKbeta
2) Confidence 0.61 Published 2004 Journal Circ. Res. Section Abstract Doc Link 14976126 Disease Relevance 0.19 Pain Relevance 0.28
Furthermore, no differences were seen in phosphorylation of GSKalpha (Ser21 or Tyr279) or phosphorylation of GSKbeta (Tyr216).
Phosphorylation (phosphorylation) of GSKbeta
3) Confidence 0.47 Published 2004 Journal Circ. Res. Section Abstract Doc Link 14976126 Disease Relevance 0.19 Pain Relevance 0.22
We next determined if the addition of TCA would result in the activation of AKT and phosphorylation of FOX01, a transcription factor known to regulate gluconeogenic genes.
Phosphorylation (phosphorylation) of factor
4) Confidence 0.02 Published 2010 Journal Journal of Lipid Research Section Body Doc Link PMC2903791 Disease Relevance 0.12 Pain Relevance 0.06

General Comments

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