INT116976

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Context Info
Confidence 0.73
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 4.10
Pain Relevance 0.94

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CCR6) plasma membrane (CCR6) signal transducer activity (CCR6)
Anatomy Link Frequency
epithelium 1
CCR6 (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 23 99.96 Very High Very High Very High
Inflammation 6 95.68 Very High Very High Very High
Crohn's disease 3 93.16 High High
spastic colon 1 79.68 Quite High
alcohol 1 67.40 Quite High
chemokine 6 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatic Cancer 62 100.00 Very High Very High Very High
Pancreatitis 26 100.00 Very High Very High Very High
Malignant Neoplastic Disease 11 100.00 Very High Very High Very High
Cystadenoma 21 99.68 Very High Very High Very High
Inflammatory Bowel Disease 13 98.96 Very High Very High Very High
Disease 9 96.04 Very High Very High Very High
INFLAMMATION 5 95.68 Very High Very High Very High
Colitis 2 94.52 High High
Cancer 17 93.52 High High
Functional Bowel Disorder 1 79.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CCL20 localized to follicle-associated epithelium, and CCR6 to the adjacent mantle zone of lymphoid follicles.
Localization (localized) of CCR6 in epithelium
1) Confidence 0.73 Published 2004 Journal J. Clin. Immunol. Section Abstract Doc Link 14997037 Disease Relevance 1.43 Pain Relevance 0.26
In summary, our findings suggest that CCR6 transcripts are up-regulated in PCA as well as in the pre-malignant pancreatic diseases CP and PA.
Localization (diseases) of CCR6 associated with malignant neoplastic disease, cystadenoma, pancreatitis, pancreatic cancer and chronic pancreatitis
2) Confidence 0.70 Published 2010 Journal J Transl Med Section Body Doc Link PMC2877001 Disease Relevance 2.67 Pain Relevance 0.67

General Comments

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