INT117436

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Context Info
Confidence 0.26
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.44
Pain Relevance 0.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (IKBKB) nucleus (IKBKB) cytoplasm (IKBKB)
Anatomy Link Frequency
amnion 1
IKBKB (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 2 97.60 Very High Very High Very High
cytokine 3 96.44 Very High Very High Very High
dexamethasone 2 95.64 Very High Very High Very High
withdrawal 3 87.12 High High
Inflammation 4 57.84 Quite High
agonist 8 5.00 Very Low Very Low Very Low
Dismenorea 3 5.00 Very Low Very Low Very Low
cva 3 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
iatrogenic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 5 97.36 Very High Very High Very High
Apoptosis 5 92.88 High High
Necrosis 3 92.12 High High
Cancer 10 91.76 High High
Carcinoma 4 91.36 High High
Pre-term Labor 37 20.56 Low Low
Premature Birth 10 12.00 Low Low
Infection 11 5.00 Very Low Very Low Very Low
Bacterial Vaginosis 6 5.00 Very Low Very Low Very Low
Infant Respiratory Distress Syndrome 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recently, the nonsteroidal anti-inflammatory drug (NSAID) sulindac and its metabolites have been shown to inhibit the NF-kappaB-mediated survival signals through inhibition of IKK-beta by their direct interaction.
IKK-beta Binding (interaction) of associated with inflammation and cinod
1) Confidence 0.26 Published 2003 Journal Ann. N. Y. Acad. Sci. Section Abstract Doc Link 15033733 Disease Relevance 1.38 Pain Relevance 0.20
expression and activity in amnion cells by blocking transcription factor binding at the nuclear factor kappa beta (NF-??)
nuclear factor kappa beta Binding (binding) of in amnion
2) Confidence 0.07 Published 2010 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2861440 Disease Relevance 0.06 Pain Relevance 0.28

General Comments

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