INT117703

Context Info Confidence 0.01 First Reported 2004 Last Reported 2004 Negated 0 Speculated 0 Reported most in Title Documents 1 Total Number 1 Disease Relevance 0.08 Pain Relevance 0.47

cytosol (JUN) nucleoplasm (JUN) nuclear chromosome (JUN) aging (JUN) nucleus (JUN) plasma membrane (OPRK1)

OPRK1 (Homo sapiens) JUN (Homo sapiens)

Pain Link Frequency Relevance Heat Kappa opioid receptor 2 100.00 opioid receptor 10 99.20 Analgesic 1 96.92 Delta opioid receptors 1 58.40

Disease Link Frequency Relevance Heat Bordatella Infection 1 79.64

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Phosphatidylinositol-3 kinase is distinctively required for mu-, but not kappa-opioid receptor-induced activation of c-Jun N-terminal kinase.

kappa-opioid receptor Positive_regulation (induced) of Positive_regulation (activation) of c-Jun associated with kappa opioid receptor

1) Confidence 0.01 Published 2004 Journal J. Neurochem. Section Title Doc Link 15056283 Disease Relevance 0.08 Pain Relevance 0.47

General Comments

This test has worked.