INT118358

From wiki-pain
Revision as of 18:49, 24 September 2012 by Daniel (Talk | contribs)

(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search
Context Info
Confidence 0.32
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.77
Pain Relevance 1.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Pag1) intracellular (Pag1)
Anatomy Link Frequency
PAG 4
neuron 2
Pag1 (Mus musculus)
Pain Link Frequency Relevance Heat
Central grey 10 100.00 Very High Very High Very High
Analgesic 1 100.00 Very High Very High Very High
GABAergic 7 98.94 Very High Very High Very High
antinociception 2 97.68 Very High Very High Very High
Antinociceptive 2 95.28 Very High Very High Very High
antagonist 2 89.20 High High
Serotonin 2 84.24 Quite High
tail-flick 2 75.76 Quite High
agonist 4 73.08 Quite High
allodynia 5 72.40 Quite High
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 26 100.00 Very High Very High Very High
Nociception 4 100.00 Very High Very High Very High
Neuropathic Pain 5 72.40 Quite High
Pain 1 37.72 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Some studies have indicated that alterations in the levels of cerebral 5-hydroxytryptamine (5-HT) mediate or modulate the analgesic effect of PAG stimulation.
Regulation (modulate) of Regulation (effect) of PAG in PAG associated with analgesic and urological neuroanatomy
1) Confidence 0.32 Published 2004 Journal Brain Res. Section Abstract Doc Link 15120594 Disease Relevance 0.64 Pain Relevance 0.34
Presynaptic kainate receptors on GABAergic nerve terminals appear to modulate GABAergic transmission, and in doing so may play an important role in the regulation of PAG neuron excitability.
Regulation (role) of Regulation (regulation) of PAG in neuron associated with gabaergic and central grey
2) Confidence 0.04 Published 2010 Journal Eur. J. Pharmacol. Section Abstract Doc Link 20303934 Disease Relevance 0.23 Pain Relevance 0.51
Thus, it is possible that endogenous RAS peptides could participate on the modulation of nociception in the PAG.
Regulation (participate) of Regulation (modulation) of PAG in PAG associated with nociception and urological neuroanatomy
3) Confidence 0.01 Published 2005 Journal Neuroscience Section Abstract Doc Link 15802196 Disease Relevance 0.90 Pain Relevance 0.59

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox