INT11888

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Context Info
Confidence 0.47
First Reported 1992
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.87
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (MUC16) extracellular region (MUC16) cell adhesion (MUC16)
plasma membrane (MUC16)
MUC16 (Homo sapiens)
Pain Link Frequency Relevance Heat
Dismenorea 2 96.44 Very High Very High Very High
imagery 4 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 273 98.76 Very High Very High Very High
Dysmenorrhea 2 96.44 Very High Very High Very High
Ovarian Cancer 112 85.48 High High
Prostate Cancer 27 26.24 Quite Low
Disease 33 7.44 Low Low
Malignant Neoplastic Disease 5 5.00 Very Low Very Low Very Low
Metastasis 4 5.00 Very Low Very Low Very Low
Anxiety Disorder 2 5.00 Very Low Very Low Very Low
Benign Prostatic Hypertrophy 2 5.00 Very Low Very Low Very Low
Recurrence 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, the performance of the best two marker combination (MUC16 and WFDC2) was not significantly different from the best single marker (MUC16) as measured by pAUC (from specificity?
Positive_regulation (performance) of Localization (performance) of MUC16
1) Confidence 0.47 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2440813 Disease Relevance 0.22 Pain Relevance 0
We conclude that significantly increased secretion of CA125 from heterotopic EC could be attributed to the increase in serum CA125 in patients with adenomyosis.
Positive_regulation (increased) of Localization (secretion) of CA125 associated with dismenorea
2) Confidence 0.41 Published 1992 Journal Nippon Sanka Fujinka Gakkai Zasshi Section Abstract Doc Link 1607752 Disease Relevance 0.19 Pain Relevance 0.19
When biomarker secretion by healthy cells is present (a more likely scenario), it was assumed that the secretion of CA125 by healthy cells accounts for up to 13.1 U/ml, and that tumor cells contribute the rest of the secretion up to the required cut-off level.
Positive_regulation (accounts) of Localization (secretion) of CA125 associated with cancer
3) Confidence 0.23 Published 2008 Journal PLoS Medicine Section Body Doc Link PMC2517618 Disease Relevance 1.46 Pain Relevance 0

General Comments

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