INT119379

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Context Info
Confidence 0.04
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.76
Pain Relevance 0.87

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Ppp2r2c)
Anatomy Link Frequency
spinal cord dorsal horn 1
Ppp2r2c (Mus musculus)
Pain Link Frequency Relevance Heat
Kinase C 1 100.00 Very High Very High Very High
Spinal cord 1 99.52 Very High Very High Very High
Demyelination 1 99.32 Very High Very High Very High
Dorsal horn 1 99.04 Very High Very High Very High
Hyperalgesia 1 98.76 Very High Very High Very High
allodynia 1 98.42 Very High Very High Very High
Calcium channel 1 97.56 Very High Very High Very High
intrathecal 1 91.28 High High
Neuropathic pain 5 90.32 High High
Peripheral nerve injury 1 67.20 Quite High
Disease Link Frequency Relevance Heat
Demyelinating Disease 1 99.32 Very High Very High Very High
Hyperalgesia 1 98.76 Very High Very High Very High
Neuropathic Pain 6 98.42 Very High Very High Very High
Nervous System Injury 2 97.84 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Wild-type animals with nerve injury develop behavioral allodynia and hyperalgesia paralleled by demyelination in the dorsal root and increased expression of both the protein kinase C gamma-isoform within the spinal cord dorsal horn and the alpha(2)delta(1) calcium channel subunit in dorsal root ganglia.
Gene_expression (expression) of gamma-isoform in spinal cord dorsal horn associated with allodynia, calcium channel, dorsal horn, spinal cord, hyperalgesia, demyelination, kinase c and nervous system injury
1) Confidence 0.04 Published 2004 Journal Nat. Med. Section Abstract Doc Link 15195086 Disease Relevance 0.76 Pain Relevance 0.87

General Comments

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