INT119455

Context Info Confidence 0.00 First Reported 2003 Last Reported 2003 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.14 Pain Relevance 0.10

RNA binding (Gtf3a) cell adhesion (Itga2b) nucleus (Gtf3a) intracellular (Gtf3a) DNA binding (Gtf3a)

Anatomy Link Frequency platelet 1 Itga2b (Mus musculus) Gtf3a (Mus musculus)

Pain Link Frequency Relevance Heat antagonist 1 75.00 Angina 1 62.16

Disease Link Frequency Relevance Heat Thrombosis 1 76.40 Cv General 3 Under Development 1 62.16

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Platelet aggregation involves the binding of adhesive proteins (fibrinogen, von Willebrand factor) to the alphaIIbbeta3 integrin, which assumes a high-affinity state for adhesive proteins during platelet activation.

alphaIIbbeta3 Binding (binding) of factor in platelet

1) Confidence 0.00 Published 2003 Journal Semin Vasc Med Section Abstract Doc Link 15199475 Disease Relevance 0.14 Pain Relevance 0.10

General Comments

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