INT119917

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Context Info
Confidence 0.01
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 1.82

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Oprd1) intracellular (Zfp821) cytoplasm (Oprd1)
signal transducer activity (Oprd1)
Anatomy Link Frequency
medulla 3
pons 1
Zfp821 (Rattus norvegicus)
Oprd1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
opioid receptor 16 100.00 Very High Very High Very High
medulla 2 100.00 Very High Very High Very High
antinociception 6 93.68 High High
tail-flick 2 91.84 High High
agonist 6 88.52 High High
mu opioid receptor 2 67.84 Quite High
antagonist 6 66.32 Quite High
Kappa opioid receptor 2 61.04 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
TAN-821 stimulated the binding of the nonhydrolyzable guanosine 5'-triphosphate analog, guanosine 5'-(gamma-thio)-triphosphate (GTPgammaS), to the mouse pons/medulla membrane via the activation of putative epsilon opioid receptor.
TAN-821 Positive_regulation (stimulated) of Positive_regulation (activation) of epsilon opioid receptor in medulla associated with medulla and opioid receptor
1) Confidence 0.01 Published 2004 Journal Bioorg. Med. Chem. Section Abstract Doc Link 15246090 Disease Relevance 0 Pain Relevance 0.91
TAN-821 stimulated the binding of the nonhydrolyzable guanosine 5'-triphosphate analog, guanosine 5'-(gamma-thio)-triphosphate (GTPgammaS), to the mouse pons/medulla membrane via the activation of putative epsilon opioid receptor.
TAN-821 Positive_regulation (stimulated) of in pons Positive_regulation (activation) of epsilon opioid receptor in medulla associated with medulla and opioid receptor
2) Confidence 0.00 Published 2004 Journal Bioorg. Med. Chem. Section Abstract Doc Link 15246090 Disease Relevance 0 Pain Relevance 0.91

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