INT120330

Context Info Confidence 0.12 First Reported 2004 Last Reported 2004 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.94

transport (Napa) vesicle-mediated transport (Napa)

Napa (Mus musculus)

Pain Link Frequency Relevance Heat Kinase C 4 99.62 Morphine 7 98.68 Hippocampus 1 69.88 Neurotransmitter 1 63.44 opiate 2 58.56

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Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

This suggests a causal relationship between the inhibition of PKC-dependent SNAP-25 phosphorylation and the down-regulation of SNARE complex formation after chronic morphine treatment.

Phosphorylation (phosphorylation) of SNARE associated with kinase c and morphine

1) Confidence 0.12 Published 2004 Journal J. Biol. Chem. Section Abstract Doc Link 15277518 Disease Relevance 0 Pain Relevance 0.94

General Comments

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