INT120366

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Context Info
Confidence 0.35
First Reported 1992
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.15
Pain Relevance 0.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Rara) nucleus (Rara) enzyme binding (Rara)
DNA binding (Rara) transcription factor binding (Rara) cytoplasm (Rara)
Rara (Mus musculus)
Pain Link Frequency Relevance Heat
lidocaine 5 99.18 Very High Very High Very High
c fibre 5 98.78 Very High Very High Very High
Disease Link Frequency Relevance Heat
Cough 1 82.72 Quite High
Paralysis 1 67.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Intravenous lidocaine (1 mg.kg(-1) or 2 mg.kg(-1)) produced a suppression of SAR activity but not of RAR activity.
Negative_regulation (suppression) of RAR associated with lidocaine
1) Confidence 0.35 Published 1992 Journal J Anesth Section Abstract Doc Link 15278511 Disease Relevance 0.08 Pain Relevance 0.43
In rats pretreated with isoproterenol (a bronchodilator), the C-fiber response was not significantly affected (Delta = -26%), the RAR response was reduced (Delta = -88%), and the Rl response was prevented.
Negative_regulation (reduced) of RAR associated with c fibre
2) Confidence 0.20 Published 2005 Journal J. Appl. Physiol. Section Abstract Doc Link 15465891 Disease Relevance 0.07 Pain Relevance 0.43

General Comments

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