INT120919

Context Info Confidence 0.01 First Reported 2004 Last Reported 2004 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.16 Pain Relevance 0

protein transporter activity (COX18) mitochondrion (COX18)

COX18 (Homo sapiens)

Pain Link Frequency Relevance Heat Inflammation 2 25.00 Pain 2 25.00 COX2 1 25.00 cOX1 1 25.00

Disease Link Frequency Relevance Heat Glioma 2 84.16 Pressure And Volume Under Development 1 25.00 INFLAMMATION 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

By immunoblotting and reverse-transcription polymerase chain reaction, we showed that gamma-mangostin concentration-dependently inhibited lipopolysaccharide (LPS)-induced expression of COX-2 protein and its mRNA, but not those of constitutive COX-1 cyclooxygenase.

Positive_regulation (-induced) of Transcription (expression) of COX-2 protein

1) Confidence 0.01 Published 2004 Journal Mol. Pharmacol. Section Abstract Doc Link 15322259 Disease Relevance 0.16 Pain Relevance 0

General Comments

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