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Context Info
Confidence 0.18
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.29
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

ribosome (Rps6ka1) nucleus (Rps6ka1) kinase activity (Rps6ka1)
transcription factor binding (Rps6ka1) cytoplasm (Rps6ka1)
Anatomy Link Frequency
cortex 1
Rps6ka1 (Mus musculus)
Pain Link Frequency Relevance Heat
Action potential 1 49.68 Quite Low
tetrodotoxin 1 46.96 Quite Low
antagonist 7 18.24 Low Low
palliative 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Bile 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 54 92.56 High High
Cancer 156 87.16 High High
Death 10 84.48 Quite High
Pressure And Volume Under Development 1 56.52 Quite High
Malignant Neoplastic Disease 5 56.20 Quite High
Metastasis 5 55.76 Quite High
Disease 6 53.16 Quite High
Hepatocellular Cancer 36 50.00 Quite Low
Pancreatic Cancer 21 50.00 Quite Low
Adenocarcinoma 11 45.88 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Activated p90Rsk can phosphorylate Bad and prevent its proapoptotic activity [61].
Positive_regulation (Activated) of p90Rsk
1) Confidence 0.18 Published 2003 Journal BMC Gastroenterol Section Body Doc Link PMC317301 Disease Relevance 0.70 Pain Relevance 0
These effects are executed through a heterotrimeric G protein-coupled receptor, which mediates Ang II transactivated epidermal growth factor (EGF)-induced activation of MEK (MAPK kinase 1) and ERK [12].
Positive_regulation (activation) of MAPK kinase 1
2) Confidence 0.17 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2846883 Disease Relevance 0.59 Pain Relevance 0
In this study, we ask: Are activated forms of ERK, RSK, and CREB colocalized in the cortex and are they coordinately regulated by synaptic signals?
Positive_regulation (activated) of RSK in cortex
3) Confidence 0.15 Published 2004 Journal J. Comp. Neurol. Section Abstract Doc Link 15389611 Disease Relevance 0 Pain Relevance 0

General Comments

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