INT121767

Context Info Confidence 0.31 First Reported 2003 Last Reported 2004 Negated 0 Speculated 0 Reported most in Abstract Documents 2 Total Number 2 Disease Relevance 0.75 Pain Relevance 0.11

ribosome (Rps6ka1) nucleus (Rps6ka1) kinase activity (Rps6ka1) transcription factor binding (Rps6ka1) cytoplasm (Rps6ka1)

Rps6ka1 (Mus musculus)

Pain Link Frequency Relevance Heat Action potential 1 77.84 tetrodotoxin 1 75.12 Bile 1 5.00 palliative 1 5.00 metalloproteinase 1 5.00 imagery 1 5.00

Disease Link Frequency Relevance Heat Apoptosis 39 88.96 Cancer 72 86.76 Death 7 85.92 Hepatocellular Cancer 36 50.00 Liver Cancer 12 32.52 Metastasis 4 31.88 Severe Combined Immunodeficiency 7 5.00 Cirrhosis 5 5.00 Disease 4 5.00 Cleidocranial Dysplasia 3 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Activated p90Rsk can phosphorylate Bad and prevent its proapoptotic activity [61].

Phosphorylation (phosphorylate) of p90Rsk

1) Confidence 0.31 Published 2003 Journal BMC Gastroenterol Section Body Doc Link PMC317301 Disease Relevance 0.75 Pain Relevance 0

Second, while phosphorylation of ERK and RSK are modulated by visual experience, phosphorylation of CREB at serines 133, 142, or 143 is detected constitutively and is unaffected by experience.

Phosphorylation (phosphorylation) of RSK

2) Confidence 0.27 Published 2004 Journal J. Comp. Neurol. Section Abstract Doc Link 15389611 Disease Relevance 0 Pain Relevance 0.11

General Comments

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