INT121772

Context Info Confidence 0.00 First Reported 2004 Last Reported 2004 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 2 Disease Relevance 0 Pain Relevance 0

ribosome (Rps6ka1) nucleus (Rps6ka1) kinase activity (Rps6ka1) transcription factor binding (Rps6ka1) cytoplasm (Rps6ka1)

Rps6ka1 (Mus musculus) USHBP1 (Homo sapiens)

Pain Link Frequency Relevance Heat Action potential 2 36.40 tetrodotoxin 2 33.68

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Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In cell culture systems, the extracellular-regulated kinase (ERK) and ribosomal S6 kinase (RSK) couple synaptic signals to CRE-mediated gene expression by modulating CRE-binding protein (CREB) phosphorylation.

ribosomal S6 kinase Regulation (modulating) of Phosphorylation (phosphorylation) of CRE-binding protein

1) Confidence 0.00 Published 2004 Journal J. Comp. Neurol. Section Abstract Doc Link 15389611 Disease Relevance 0 Pain Relevance 0

In cell culture systems, the extracellular-regulated kinase (ERK) and ribosomal S6 kinase (RSK) couple synaptic signals to CRE-mediated gene expression by modulating CRE-binding protein (CREB) phosphorylation.

RSK Regulation (modulating) of Phosphorylation (phosphorylation) of CRE-binding protein

2) Confidence 0.00 Published 2004 Journal J. Comp. Neurol. Section Abstract Doc Link 15389611 Disease Relevance 0 Pain Relevance 0

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