INT122539

Context Info Confidence 0.24 First Reported 2004 Last Reported 2004 Negated 1 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0

extracellular space (FGF2, IL6) extracellular region (FGF2, IL6) signal transduction (FGF2) aging (IL6) nucleus (FGF2) cytoplasm (FGF2)

FGF2 (Homo sapiens) IL6 (Homo sapiens)

Pain Link Frequency Relevance Heat Chronic pancreatitis 1 5.00

Disease Link Frequency Relevance Heat Pancreatitis 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

FGF-2 induced AP-1 DNA-binding activity, but blockage of AP-1 signaling by adenovirus-mediated transfer of a dominant negative c-Jun gene did not affect FGF-2-induced IL-6 mRNA expression.

FGF-2 Neg (not) Regulation (affect) of Transcription (expression) of IL-6

1) Confidence 0.24 Published 2004 Journal Pancreas Section Body Doc Link 15502643 Disease Relevance 0 Pain Relevance 0

General Comments

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