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Context Info
Confidence 0.21
First Reported 2004
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 3.52
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (TNF, Tnfrsf11b) extracellular region (TNF, Tnfrsf11b) extracellular matrix organization (TNF, Tnfrsf11b)
extracellular space (TNF) proteinaceous extracellular matrix (Tnfrsf11b) plasma membrane (TNF)
TNF (Homo sapiens)
Tnfrsf11b (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 6 100.00 Very High Very High Very High
Pain 2 79.08 Quite High
metalloproteinase 1 29.68 Quite Low
Inflammation 6 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
beta blocker 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Necrosis 1 99.80 Very High Very High Very High
Apoptosis 7 99.64 Very High Very High Very High
Cancer 8 99.62 Very High Very High Very High
Death 2 96.44 Very High Very High Very High
Breast Cancer 10 94.40 High High
Calcification 59 93.92 High High
Atherosclerosis 19 91.44 High High
Bone Cancer 4 89.48 High High
Atherosclerotic Plaque 12 87.52 High High
Metastasis 3 81.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The potential survival effects of OPG are mediated through binding to a member of the TNF super family, TNF-related Apoptosis Inducing Ligand (TRAIL), preventing association between TRAIL and its death-inducing receptors present on a number of tumour cell types.
TNF Binding (binding) of OPG associated with cancer, apoptosis and death
1) Confidence 0.21 Published 2004 Journal Breast Cancer Res. Treat. Section Abstract Doc Link 15567943 Disease Relevance 1.32 Pain Relevance 0.08
The potential survival effects of OPG are mediated through binding to a member of the TNF super family, TNF-related Apoptosis Inducing Ligand (TRAIL), preventing association between TRAIL and its death-inducing receptors present on a number of tumour cell types.
TNF Binding (binding) of OPG associated with cancer, apoptosis and death
2) Confidence 0.21 Published 2004 Journal Breast Cancer Res. Treat. Section Abstract Doc Link 15567943 Disease Relevance 1.33 Pain Relevance 0.08
called tumor necrosis factor- [TNF-] related activation-induced cytokine

(TRANCE) or osteoprotegerin ligand (OPGL) [84], is also necessary and

TNF Binding (ligand) of osteoprotegerin associated with necrosis, cancer and cytokine
3) Confidence 0.02 Published 2007 Journal Clinical and Developmental Immunology Section Body Doc Link PMC2248226 Disease Relevance 0.87 Pain Relevance 0.08

General Comments

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