INT124378

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Context Info
Confidence 0.00
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.59
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ctnnb1) mitochondrion (Prodh2) enzyme binding (Ctnnb1)
DNA binding (Ctnnb1) protein complex (Ctnnb1) cytoplasm (Ctnnb1)
Prodh2 (Mus musculus)
Ctnnb1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Abeta 3 97.84 Very High Very High Very High
cINOD 1 90.84 High High
Inflammation 2 90.36 High High
Neurotransmitter 1 83.28 Quite High
Disease Link Frequency Relevance Heat
Toxicity 1 97.60 Very High Very High Very High
Drug Induced Neurotoxicity 2 95.68 Very High Very High Very High
INFLAMMATION 2 90.36 High High
Alzheimer's Dementia 3 81.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IBU-PO (0.01-1 microM) inhibits glycogen-synthase-kinase-3beta (GSK-3beta) and stabilizes cytoplasmic beta-catenin reverting the silencing of the Wnt pathway caused by Abeta-toxicity and GSK-3beta overexpression.
IBU-PO Positive_regulation (stabilizes) of cytoplasmic beta-catenin associated with toxicity and abeta
1) Confidence 0.00 Published 2005 Journal Neurobiol. Dis. Section Abstract Doc Link 15649708 Disease Relevance 0.59 Pain Relevance 0.35

General Comments

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