INT127238

Context Info Confidence 0.00 First Reported 2005 Last Reported 2005 Negated 0 Speculated 0 Reported most in Title Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.56

nucleus (Rtcd1) molecular_function (Rtcd1) ligase activity (Rtcd1)

Rtcd1 (Mus musculus)

Pain Link Frequency Relevance Heat Morphine 7 99.20 Kinase C 3 98.48 Potency 1 95.68 opioid receptor 1 78.92 Opioid 1 22.28 tolerance 1 22.00

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Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Chronic morphine acts via a protein kinase Cgamma-G(beta)-adenylyl cyclase complex to augment phosphorylation of G(beta) and G(betagamma) stimulatory adenylyl cyclase signaling.

Positive_regulation (augment) of Phosphorylation (phosphorylation) of cyclase associated with morphine

1) Confidence 0.00 Published 2005 Journal Brain Res. Mol. Brain Res. Section Title Doc Link 15908039 Disease Relevance 0 Pain Relevance 0.56

General Comments

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