INT127584

Context Info Confidence 0.00 First Reported 2005 Last Reported 2005 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.60 Pain Relevance 0.75

cell differentiation (Ctbp1) aging (CNR1) transferase activity, transferring acyl groups (Ctbp1) cytoplasm (Ctbp1) response to stress (CNR1) signal transducer activity (CNR1)

CNR1 (Homo sapiens) Ctbp1 (Rattus norvegicus)

Pain Link Frequency Relevance Heat Cannabinoid receptor 2 100.00 Neuropathic pain 1 98.64 Analgesic 3 97.48 agonist 2 92.96 IPN 2 82.88 Cannabinoid 4 75.00 Antihyperalgesic 2 75.00 Hyperalgesia 1 73.76 antagonist 2 67.04 analgesia 1 50.08

Disease Link Frequency Relevance Heat Neuropathic Pain 3 98.64 Inflammatory Pain 2 82.88 Hyperalgesia 1 73.76 Catalepsy 1 55.60 Hypothermia 1 51.92 Pain 2 45.04

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Here we show that CT-3 binds to human cannabinoid receptors in vitro, with high affinity at hCB1 (Ki 6 nM) and hCB2 (Ki 56 nM) receptors.

hCB1 Binding (binds) of CT-3 associated with cannabinoid receptor

1) Confidence 0.00 Published 2005 Journal Pain Section Abstract Doc Link 15936883 Disease Relevance 0.60 Pain Relevance 0.75

General Comments

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