INT128684

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Context Info
Confidence 0.00
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 2.46
Pain Relevance 0.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (RETNLB) protein modification process (TGM1) extracellular region (RETNLB)
molecular_function (RETNLB) transferase activity, transferring acyl groups (TGM1) cellular_component (RETNLB)
TGM1 (Homo sapiens)
RETNLB (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 2 100.00 Very High Very High Very High
spastic colon 6 99.34 Very High Very High Very High
Inflammatory response 2 93.92 High High
cytokine 1 75.12 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 4 100.00 Very High Very High Very High
Toxicity 2 99.82 Very High Very High Very High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

5 99.34 Very High Very High Very High
Enteritis 5 99.20 Very High Very High Very High
Celiac Disease 9 98.84 Very High Very High Very High
Injury 2 97.36 Very High Very High Very High
Hepatotoxicity 1 95.48 Very High Very High Very High
Diarrhoea 1 86.92 High High
Functional Bowel Disorder 1 78.12 Quite High
Liver Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We hypothesize that other factors, unique to CD not present in TS or IBS-D, like gluten toxicity and the presence of tissular transglutaminase (tTG) an auto-antigen with pro-inflammatory and remodeling properties, act in addition to intestinal mucosal injury and account to hypertransaminasemia in CD.
tissular transglutaminase Binding (presence) of pro-inflammatory associated with toxicity, celiac disease, inflammation, enteritis, spastic colon and injury
1) Confidence 0.00 Published 2005 Journal Med. Hypotheses Section Abstract Doc Link 16023789 Disease Relevance 2.02 Pain Relevance 0.72

General Comments

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