INT129434

Context Info Confidence 0.00 First Reported 2005 Last Reported 2005 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.29

extracellular space (Oxt) extracellular region (Oxt) molecular_function (C1r) cellular_component (C1r) cytoplasm (Oxt) biological_process (C1r)

C1r (Rattus norvegicus) Oxt (Mus musculus)

Pain Link Frequency Relevance Heat agonist 1 99.16 opioid receptor 2 98.84 Opioid 1 98.84 MU agonist 1 56.08 Neurotransmitter 1 35.84 Central nervous system 1 34.16 Neuropeptide 2 25.00

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Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Because the R-type component of the neurophypophysial terminal Ca2+ current (ICa) mediates exclusively oxytocin release, we hypothesised that micro-opioids could preferentially inhibit oxytocin release by blocking this channel subtype.

R-type component Positive_regulation (mediates) of Localization (release) of oxytocin associated with opioid

1) Confidence 0.00 Published 2005 Journal J. Neuroendocrinol. Section Abstract Doc Link 16101897 Disease Relevance 0 Pain Relevance 0.29

General Comments

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