INT129586

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Context Info
Confidence 0.53
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.83
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

unfolded protein binding (St13) protein folding (St13) cytosol (St13)
protein complex (St13) cytoplasm (St13)
Anatomy Link Frequency
liver 4
neurons 2
St13 (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 3 82.80 Quite High
Paracetamol 6 75.00 Quite High
Dopamine 18 68.60 Quite High
midbrain 3 56.24 Quite High
Substantia nigra 18 53.84 Quite High
Central nervous system 9 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Liver Cancer 2 99.84 Very High Very High Very High
Targeted Disruption 31 95.92 Very High Very High Very High
Injury 2 75.00 Quite High
Severe Combined Immunodeficiency 2 71.68 Quite High
Cancer 5 28.24 Quite Low
Necrosis 2 27.76 Quite Low
Overdose 2 25.00 Low Low
Hepatitis 2 25.00 Low Low
Parkinson's Disease 15 5.00 Very Low Very Low Very Low
Infection 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
HIP/PAP is overexpressed in liver carcinoma; however, its functional role remains unclear.
Positive_regulation (overexpressed) of Gene_expression (overexpressed) of HIP/PAP in liver associated with liver cancer
1) Confidence 0.53 Published 2005 Journal Hepatology Section Abstract Doc Link 16116631 Disease Relevance 0.32 Pain Relevance 0.07
HIP/PAP is overexpressed in liver carcinoma; however, its functional role remains unclear.
Positive_regulation (overexpressed) of Gene_expression (overexpressed) of HIP/PAP in liver associated with liver cancer
2) Confidence 0.38 Published 2005 Journal Hepatology Section Abstract Doc Link 16116631 Disease Relevance 0.32 Pain Relevance 0.07
5.1±0.3), consistent with increased transduction of TH neurons in the SNc (Figure 4).


Positive_regulation (increased) of Gene_expression (transduction) of SNc in neurons
3) Confidence 0.03 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2941453 Disease Relevance 0.18 Pain Relevance 0.13

General Comments

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