INT129993

Context Info Confidence 0.20 First Reported 2005 Last Reported 2005 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 1.16 Pain Relevance 0.15

Anatomy Link Frequency nociceptor 1 Igha (Mus musculus)

Pain Link Frequency Relevance Heat nociceptor 1 100.00 Inflammatory response 1 97.44

Disease Link Frequency Relevance Heat Cramps 1 98.24 Urological Neuroanatomy 1 97.92 INFLAMMATION 1 97.24 Phenylketonuria 8 92.60 Congenital Anomalies 1 77.12 Cognitive Disorder 1 68.24 Pigment Disorder 1 66.12 Dementia 1 65.24 Metabolic Disorder 1 59.84

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Four are involved in defense and inflammatory responses of neutrophils (NE, MPO, NGP, and CRAMP), three other overexpressed genes are related to extracellular matrix organization and degradation (COL1A1, COL1A2, and MMP13); the remainder were a nociceptor in sensory neurons (MrgA1), a structural gene of P lysozyme (Lzp-s), an immunoglobulin alpha heavy chain constant region gene (Igh-2), an osteocalcin-related protein precursor (Bglap-rs1), and a membrane-spanning 4 domain, subfamily A, member 3 (Ms4a3).

Protein_catabolism (degradation) of Igh-2 in nociceptor associated with cramps, inflammatory response, nociceptor and urological neuroanatomy

1) Confidence 0.20 Published 2005 Journal Mol. Genet. Metab. Section Abstract Doc Link 16150627 Disease Relevance 1.16 Pain Relevance 0.15

General Comments

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