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Context Info
Confidence 0.49
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 2.54
Pain Relevance 1.01

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Crp)
Anatomy Link Frequency
platelet 4
Crp (Mus musculus)
Pain Link Frequency Relevance Heat
spinal inflammation 9 99.02 Very High Very High Very High
Adalimumab 57 93.16 High High
Inflammation 23 84.16 Quite High
psoriasis 6 79.52 Quite High
spondylitis 1 67.36 Quite High
Arthritis 46 50.00 Quite Low
Angina 3 50.00 Quite Low
cytokine 2 45.52 Quite Low
Inflammatory response 3 9.44 Low Low
rheumatoid arthritis 10 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoporosis 4 99.56 Very High Very High Very High
Low Back Pain 10 99.02 Very High Very High Very High
Disease 20 97.52 Very High Very High Very High
Myocardial Infarction 61 92.84 High High
Hypercalcemia 1 85.04 High High
INFLAMMATION 27 84.16 Quite High
Psoriasis 7 79.52 Quite High
Necrosis 4 75.88 Quite High
Cancer 2 75.52 Quite High
Stroke 12 73.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
There is an association between elevated CRP and more pronounced platelet aggregation as well as high residual platelet reactivity, the latter assessed using PFA-100.
Positive_regulation (elevated) of CRP Binding (association) of in platelet
1) Confidence 0.49 Published 2009 Journal Thromb J Section Body Doc Link PMC2715384 Disease Relevance 0.25 Pain Relevance 0.04
For placebo-treated patients, the strongest positive associations with radiographic progression (that is, greatest odds ratio (OR)) were observed for baseline CRP as a dichotomous variable (at CRP thresholds > 0.287 mg/dl, ?
Positive_regulation (variable) of CRP Binding (associations) of
2) Confidence 0.42 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2911906 Disease Relevance 0.14 Pain Relevance 0.29
AS patients with osteoporosis showed significantly increased CRP, ESR, cross-links and PTH and a significantly decreased 1.25 D3.
Positive_regulation (increased) of CRP Binding (cross-links) of associated with spinal inflammation and osteoporosis
3) Confidence 0.19 Published 2005 Journal Osteoporos Int Section Abstract Doc Link 16172800 Disease Relevance 1.75 Pain Relevance 0.68
Interaction between CPC and hsCRP
Positive_regulation (between) of hsCRP Binding (Interaction) of
4) Confidence 0.06 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2901328 Disease Relevance 0.33 Pain Relevance 0
RESULTS: Patients with UA showed higher circulating TPO levels, as well as increased monocyte-platelet binding, platelet P-selectin expression, and CRP levels, than those with SA and healthy control subjects.
Positive_regulation (increased) of CRP Binding (binding) of in platelet
5) Confidence 0.05 Published 2006 Journal J. Am. Coll. Cardiol. Section Body Doc Link 17161245 Disease Relevance 0.07 Pain Relevance 0

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