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Context Info
Confidence 0.45
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.61
Pain Relevance 0.81

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (VTCN1)
Anatomy Link Frequency
monocytes 1
T cell 1
VTCN1 (Homo sapiens)
Pain Link Frequency Relevance Heat
melanocortin 1 receptor 12 98.82 Very High Very High Very High
chemokine 8 97.64 Very High Very High Very High
cytokine 7 97.44 Very High Very High Very High
palliative 1 75.68 Quite High
Pain 2 41.44 Quite Low
imagery 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
pain flank 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Metastasis 5 97.48 Very High Very High Very High
Alagille Syndrome 1 94.56 High High
Myeloid Leukemia 41 92.24 High High
Cancer 108 89.76 High High
Renal Cancer 87 88.64 High High
Toxicity 4 85.36 High High
Recurrence 13 83.28 Quite High
Leukemia 14 66.00 Quite High
Fever 2 54.60 Quite High
Hematological Disease 1 52.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Lack of B7H1 and B7H4 expression is a strong predictor of overall survival in patients without metastases [25-28].
Gene_expression (expression) of B7H4 associated with metastasis
1) Confidence 0.45 Published 2009 Journal Mol Cancer Section Body Doc Link PMC2667482 Disease Relevance 0.96 Pain Relevance 0
These cells show dendritic morphology, increased expression of T cell costimulatory molecule, increased antigen-presenting capacity and a constitutive chemokine release profile consistent with a dendritic cell phenotype [89, 90].
Gene_expression (expression) of costimulatory molecule in T cell associated with chemokine
2) Confidence 0.11 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2896720 Disease Relevance 0.55 Pain Relevance 0.22
Human PBMCs, including monocytes, express the melanocortin 1 receptor (MC1R), and it is thought that the ability of alphaMSH to alter monocyte-costimulatory molecule expression and IL-10 release is mediated by this receptor.
Gene_expression (expression) of monocyte-costimulatory molecule in monocytes associated with melanocortin 1 receptor
3) Confidence 0.03 Published 2005 Journal J. Immunol. Section Abstract Doc Link 16177130 Disease Relevance 0.09 Pain Relevance 0.59

General Comments

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