INT130694

Context Info Confidence 0.65 First Reported 2006 Last Reported 2006 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.77 Pain Relevance 0.44

RNA binding (Eif2s1) nucleus (Eif2s1) translation (Eif2s1) cytoplasm (Eif2s1)

Eif2s1 (Mus musculus)

Pain Link Frequency Relevance Heat cINOD 6 82.96

Disease Link Frequency Relevance Heat Cancer 4 93.76 Apoptosis 7 89.84 Stomach Cancer 1 81.88 INFLAMMATION 1 65.56

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Celecoxib caused phosphorylation of eukaryotic translation initiation factor 2 kinase (PERK) and eukaryotic initiation factor-2alpha (eIF2alpha) and production of activating transcription factor (ATF)4 mRNA.

Gene_expression (production) of eIF2alpha

1) Confidence 0.65 Published 2006 Journal Oncogene Section Abstract Doc Link 16205636 Disease Relevance 0.77 Pain Relevance 0.44

General Comments

This test has worked.