INT130765

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Context Info
Confidence 0.49
First Reported 2005
Last Reported 2009
Negated 2
Speculated 0
Reported most in Body
Documents 7
Total Number 9
Disease Relevance 7.07
Pain Relevance 1.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (ERAL1) RNA binding (ERAL1) rRNA binding (ERAL1)
intracellular (ERAL1) ribosome biogenesis (ERAL1)
Anatomy Link Frequency
chest 2
anterior 1
ERAL1 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 287 100.00 Very High Very High Very High
Angina 6 99.76 Very High Very High Very High
Osteoarthritis 96 99.64 Very High Very High Very High
palliative 2 94.48 High High
ischemia 1 87.52 High High
Inflammation 48 74.72 Quite High
cytokine 24 71.68 Quite High
tolerance 3 58.00 Quite High
Arthritis 6 50.00 Quite Low
Inflammatory response 3 31.24 Quite Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 422 100.00 Very High Very High Very High
Skin Cancer 8 99.90 Very High Very High Very High
Angina 4 99.76 Very High Very High Very High
Frailty 102 99.64 Very High Very High Very High
Disorder Of Lipid Metabolism 43 99.58 Very High Very High Very High
Renal Failure 4 99.04 Very High Very High Very High
Heart Rate Under Development 2 98.76 Very High Very High Very High
Necrosis 9 98.20 Very High Very High Very High
Myocardial Infarction 5 95.92 Very High Very High Very High
Disease Progression 18 87.28 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CONCLUSIONS: In the DES era, although most patients with ISR have stable symptoms, myocardial infarction occurred in 10%, suggesting that ISR is not a benign clinical entity.
Positive_regulation (occurred) of era
1) Confidence 0.49 Published 2008 Journal J Invasive Cardiol Section Body Doc Link 18688064 Disease Relevance 0.07 Pain Relevance 0
Predictive power of ejection fraction and renal failure in patients admitted for chest pain without ST elevation in the troponin era.
Neg (without) Positive_regulation (elevation) of era in chest associated with angina and renal failure
2) Confidence 0.45 Published 2005 Journal Am. Heart J. Section Title Doc Link 16209962 Disease Relevance 0.59 Pain Relevance 0.10
Predictive power of systolic function and congestive heart failure in patients with patients admitted for chest pain without ST elevation in the troponin era.
Neg (without) Positive_regulation (elevation) of era in chest associated with heart rate under development and angina
3) Confidence 0.45 Published 2008 Journal Am. Heart J. Section Title Doc Link 18657664 Disease Relevance 0.39 Pain Relevance 0.14
According to our results, the low baseline levels of HDL-cholesterol and HDL-Lp-PLA2 activity in ERA patients are significantly increased after immunointervention, a phenomenon that could be at least partially attributed to the immunointervention-induced reduction in cholesterol ester transferring protein activity [23].
Positive_regulation (increased) of ERA associated with rheumatoid arthritis and disorder of lipid metabolism
4) Confidence 0.17 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC1860077 Disease Relevance 1.30 Pain Relevance 0.12
Although Orringer's technique requires manual sewing in the final anterior closure of the CEGA, this did not increase leakage rates after esophageal resection of squamous cell carcinomas.
Positive_regulation (requires) of CEGA in anterior associated with skin cancer
5) Confidence 0.14 Published 2006 Journal Journal of Korean Medical Science Section Body Doc Link PMC2721924 Disease Relevance 0.36 Pain Relevance 0
All 13 patients were diagnosed with esophageal squamous cell carcinoma and underwent curative CEGA.
Positive_regulation (underwent) of CEGA associated with skin cancer
6) Confidence 0.13 Published 2006 Journal Journal of Korean Medical Science Section Body Doc Link PMC2721924 Disease Relevance 0.78 Pain Relevance 0.17
Phosphorylation-activation of PB cell subsets in ERA, RA and OA
Positive_regulation (activation) of ERA associated with rheumatoid arthritis and osteoarthritis
7) Confidence 0.06 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2724743 Disease Relevance 1.15 Pain Relevance 0.38
and STAT1) were significantly activated in the PBMC of ERA patients compared with healthy individuals.
Positive_regulation (activated) of ERA associated with rheumatoid arthritis
8) Confidence 0.06 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2724743 Disease Relevance 1.44 Pain Relevance 0.38
, p-STAT1, p-STAT3, p-STAT6 and p-ZAP70 mean fluorescent intensity (MFI) levels were significantly elevated in ERA patient PB subsets in all three cellular compartments.
Positive_regulation (elevated) of ERA associated with rheumatoid arthritis
9) Confidence 0.06 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2724743 Disease Relevance 1.00 Pain Relevance 0.26

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