INT130931

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Context Info
Confidence 0.01
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.52
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Egr1) intracellular (Egr1) DNA binding (Egr1)
transcription factor binding (Egr1) cytoplasm (Egr1)
Sis (Mus musculus)
Egr1 (Mus musculus)
Pain Link Frequency Relevance Heat
cINOD 5 93.24 High High
Disease Link Frequency Relevance Heat
Adenocarcinoma 1 96.20 Very High Very High Very High
Cancer 6 93.56 High High
INFLAMMATION 1 90.28 High High
Metastasis 1 79.76 Quite High
Polyps 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Overexpression of Egr-1 reduced cellular invasion in the Matrigel system, whereas suppression of Egr-1 by small interference RNA (siRNA) attenuated the inhibition of Matrigel invasion by these compounds, indicating that Egr-1 is responsible for the decrease in invasion reported following treatment with NSAIDs.
siRNA Negative_regulation (suppression) of Egr-1 associated with cinod
1) Confidence 0.01 Published 2005 Journal Mol. Cancer Ther. Section Abstract Doc Link 16227405 Disease Relevance 0.52 Pain Relevance 0.27

General Comments

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