INT132662

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Context Info
Confidence 0.31
First Reported 2005
Last Reported 2010
Negated 2
Speculated 1
Reported most in Body
Documents 11
Total Number 12
Disease Relevance 14.41
Pain Relevance 0.73

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
heart 1
Hcm (Mus musculus)
Pain Link Frequency Relevance Heat
beta blocker 12 92.40 High High
cva 4 89.56 High High
antagonist 10 84.96 Quite High
Calcium channel 3 80.56 Quite High
imagery 17 79.08 Quite High
ischemia 16 78.92 Quite High
Angina 16 71.76 Quite High
Serotonin 48 50.00 Quite Low
positron emission tomography 1 44.96 Quite Low
fibrosis 15 16.24 Low Low
Disease Link Frequency Relevance Heat
Hypertrophic Cardiomyopathy 441 100.00 Very High Very High Very High
Myocardial Infarction 107 100.00 Very High Very High Very High
Systemic Lupus Erythematosus 7 100.00 Very High Very High Very High
Infarction 12 99.70 Very High Very High Very High
Aneurism 85 99.48 Very High Very High Very High
Cardiovascular Disease 13 98.32 Very High Very High Very High
Disease 87 97.88 Very High Very High Very High
Increased Venous Pressure Under Development 6 97.16 Very High Very High Very High
Arrhythmias 2 Under Development 32 96.40 Very High Very High Very High
Hypertension 24 96.40 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In adult HCM patients, living with HCM has been reported to be associated with decreased levels of self reported health status compared to the general population [17], and one study also reported problems for the patients to adjust to the diagnosis [18].
HCM Binding (living) of associated with hypertrophic cardiomyopathy
1) Confidence 0.31 Published 2010 Journal BMC Med Genet Section Body Doc Link PMC2836315 Disease Relevance 0.57 Pain Relevance 0
There appears to have been a chance association between SLE and HCM, considering the clinical courses in reported cases and the pathological findings in our case.
HCM Binding (association) of associated with hypertrophic cardiomyopathy and systemic lupus erythematosus
2) Confidence 0.31 Published 2005 Journal Nihon Rinsho Meneki Gakkai Kaishi Section Abstract Doc Link 16394645 Disease Relevance 1.50 Pain Relevance 0.10
Real time 3-dimensional echocardiography has been applied to determine LV mass, but there is a paucity of data about its accuracy in HCM.
HCM Binding (accuracy) of associated with hypertrophic cardiomyopathy
3) Confidence 0.21 Published 2010 Journal Cardiovasc Ultrasound Section Body Doc Link PMC2848131 Disease Relevance 1.61 Pain Relevance 0.14
Apical infarction is not a rare finding in patients with mid-ventricular HCM.
HCM Neg (not) Spec (finding) Binding (finding) of associated with hypertrophic cardiomyopathy and infarction
4) Confidence 0.16 Published 2006 Journal Cardiovasc Ultrasound Section Body Doc Link PMC1501052 Disease Relevance 1.32 Pain Relevance 0.10
Apical HCM is unusual and mid-ventricular HCM is the most infrequent presentation, but both variants may be associated to an apical aneurysm.
HCM Binding (associated) of associated with hypertrophic cardiomyopathy and aneurism
5) Confidence 0.16 Published 2006 Journal Cardiovasc Ultrasound Section Abstract Doc Link PMC1501052 Disease Relevance 1.41 Pain Relevance 0
To the best of our knowledge, no cases of combined subaortic and mid-ventricular obstructive HCM, associated with apical aneurysm have been described.
HCM Binding (associated) of associated with hypertrophic cardiomyopathy and aneurism
6) Confidence 0.15 Published 2006 Journal Cardiovasc Ultrasound Section Body Doc Link PMC1501052 Disease Relevance 1.33 Pain Relevance 0.17
Several reports have shown an association of mid-ventricular and apical HCM with apical aneurysms [3-5].
HCM Binding (association) of associated with hypertrophic cardiomyopathy and aneurism
7) Confidence 0.15 Published 2006 Journal Cardiovasc Ultrasound Section Body Doc Link PMC1501052 Disease Relevance 1.36 Pain Relevance 0.10
Some authors did not find a significant association between this allele and the risk for HCM [35].
HCM Neg (not) Binding (association) of associated with hypertrophic cardiomyopathy
8) Confidence 0.14 Published 2010 Journal J Transl Med Section Body Doc Link PMC2907326 Disease Relevance 0.79 Pain Relevance 0
However, our definition of familial HCM was incomplete because in 19% of our patients who did not have a family history of the disease we could not exclude the presence of asymptomatic LVH in their parents.
HCM Binding (definition) of associated with left ventricular hypertrophy, hypertrophic cardiomyopathy and disease
9) Confidence 0.11 Published 2010 Journal J Transl Med Section Body Doc Link PMC2907326 Disease Relevance 0.60 Pain Relevance 0
Patients with relatives who had also been diagnosed with HCM and/or sudden cardiac death (SCD) were classified as familial cases.
HCM Binding (diagnosed) of associated with hypertrophic cardiomyopathy and myocardial infarction
10) Confidence 0.11 Published 2010 Journal J Transl Med Section Body Doc Link PMC2907326 Disease Relevance 1.47 Pain Relevance 0.07
Recognition of the heterogeneous pathophysiology of heart failure in HCM is relevant, given the targeted management strategies necessary in this disease.



HCM Binding (Recognition) of in heart associated with hypertrophic cardiomyopathy, disease and myocardial infarction
11) Confidence 0.03 Published 2010 Journal European Heart Journal Section Abstract Doc Link PMC2930982 Disease Relevance 1.58 Pain Relevance 0
In 2005, a mutation in FXN-encoded frataxin was described in a patient with HCM.
HCM Binding (patient) of associated with hypertrophic cardiomyopathy
12) Confidence 0.02 Published 2008 Journal Indian Pacing and Electrophysiology Journal Section Body Doc Link PMC2363724 Disease Relevance 0.87 Pain Relevance 0.04

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