INT132683

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Context Info
Confidence 0.00
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.93
Pain Relevance 1.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Grin2a) extracellular region (Bdnf) plasma membrane (Grin2a)
cytoplasmic membrane-bounded vesicle (Bdnf) locomotion (Grin2a)
Anatomy Link Frequency
RVM 2
Bdnf (Rattus norvegicus)
Grin2a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Rostral ventromedial medulla 7 99.84 Very High Very High Very High
nMDA receptor 1 97.84 Very High Very High Very High
IPN 1 93.32 High High
Inflammation 1 89.20 High High
Central grey 4 86.20 High High
Spinal cord 1 85.68 High High
Lasting pain 1 85.52 High High
Pain 6 80.76 Quite High
central pain 1 75.44 Quite High
Disease Link Frequency Relevance Heat
Nociception 1 96.32 Very High Very High Very High
Inflammatory Pain 1 93.32 High High
INFLAMMATION 1 89.20 High High
Urological Neuroanatomy 4 86.20 High High
Pain 5 84.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In vitro studies with RVM slices show that BDNF induces tyrosine phosphorylation of the NMDAR NR2A subunit in RVM via a signal transduction cascade involving IP(3), PKC, and Src.
BDNF Positive_regulation (induces) of Phosphorylation (phosphorylation) of NMDAR NR2A subunit in RVM associated with rostral ventromedial medulla
1) Confidence 0.00 Published 2006 Journal J. Neurosci. Section Abstract Doc Link 16399679 Disease Relevance 0.93 Pain Relevance 1.11

General Comments

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