INT134019

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Context Info
Confidence 0.12
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.66

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
neurons 2
Kcnk2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dopamine 3 100.00 Very High Very High Very High
cocaine 2 99.80 Very High Very High Very High
opioid receptor 9 98.40 Very High Very High Very High
Opioid 1 95.84 Very High Very High Very High
addiction 1 93.72 High High
Neurotransmitter 1 92.00 High High
Delta opioid receptors 1 75.00 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In support of this, cocaine-mediated increases in activation of dopamine D1 receptors (D1R) results in a desensitization of delta-opioid receptor (DOR) signaling through adenylyl cyclase (AC) in striatal neurons.
Positive_regulation (increases) of Positive_regulation (activation) of D1R in neurons associated with dopamine, opioid receptor and cocaine
1) Confidence 0.12 Published 2006 Journal Neurosci. Lett. Section Abstract Doc Link 16517070 Disease Relevance 0 Pain Relevance 0.66

General Comments

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