INT134399

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Context Info
Confidence 0.39
First Reported 2006
Last Reported 2006
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.14
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (MAPK3, MAPK8) mitochondrion (MAPK3, MAPK8) cytoplasm (MAPK3, MAPK8)
cytosol (MAPK3, MAPK8) nucleus (MAPK3, MAPK8) Golgi apparatus (MAPK3)
MAPK3 (Homo sapiens)
MAPK8 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 2 67.84 Quite High
Disease Link Frequency Relevance Heat
Apoptosis 5 100.00 Very High Very High Very High
Colon Cancer 6 96.60 Very High Very High Very High
Cancer 3 68.80 Quite High
INFLAMMATION 2 67.64 Quite High
Death 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Inhibition of ERK1/2 with U0126 induces apoptosis but fails to activate JNK phosphorylation or down-regulate beta-catenin protein expression.
Negative_regulation (Inhibition) of ERK1 Neg (fails) Positive_regulation (activate) of Phosphorylation (phosphorylation) of JNK associated with apoptosis
1) Confidence 0.39 Published 2006 Journal Mol. Cancer Ther. Section Abstract Doc Link 16546990 Disease Relevance 1.14 Pain Relevance 0.13

General Comments

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