INT134679

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Context Info
Confidence 0.01
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.56
Pain Relevance 1.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (FSCN1, MAPK8) nucleoplasm (MAPK8) mitochondrion (MAPK8)
protein binding, bridging (FSCN1) response to stress (MAPK8) cell proliferation (FSCN1)
Anatomy Link Frequency
spinal cord 1
FSCN1 (Homo sapiens)
MAPK8 (Homo sapiens)
Pain Link Frequency Relevance Heat
Spinal nerve ligature 10 100.00 Very High Very High Very High
Spinal cord 2 98.44 Very High Very High Very High
Neuropathic pain 6 98.12 Very High Very High Very High
intrathecal 3 84.00 Quite High
Pain 1 77.52 Quite High
allodynia 5 75.00 Quite High
c fibre 1 37.20 Quite Low
neuralgia 3 25.00 Low Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 11 98.12 Very High Very High Very High
Pain 1 77.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SNL induced a slow (>3 d) and persistent (>21 d) activation of JNK, in particular JNK1, in GFAP-expressing astrocytes in the spinal cord.
SNL Positive_regulation (activation) of JNK1 in spinal cord associated with spinal nerve ligature and spinal cord
1) Confidence 0.01 Published 2006 Journal J. Neurosci. Section Abstract Doc Link 16571763 Disease Relevance 0.56 Pain Relevance 1.39

General Comments

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