INT135471

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Context Info
Confidence 0.49
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (CYP2B6, UGT2B7) small molecule metabolic process (CYP2B6) lipid metabolic process (UGT2B7)
CYP2B6 (Homo sapiens)
UGT2B7 (Homo sapiens)
Pain Link Frequency Relevance Heat
Morphine 22 94.60 High High
Codeine 2 25.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since our recent research suggested that cytochrome P450s (P450s) interact with UGT2B7 to affect its function [Takeda S et al. (2005) Mol Pharmacol 67:665-672], P450 inhibitors are expected to modulate UGT2B7-catalyzed activity.
P450s Binding (interact) of UGT2B7
1) Confidence 0.49 Published 2006 Journal Drug Metab. Dispos. Section Abstract Doc Link 16679387 Disease Relevance 0 Pain Relevance 0.31
Since our recent research suggested that cytochrome P450s (P450s) interact with UGT2B7 to affect its function [Takeda S et al. (2005) Mol Pharmacol 67:665-672], P450 inhibitors are expected to modulate UGT2B7-catalyzed activity.
P450s Binding (interact) of UGT2B7
2) Confidence 0.42 Published 2006 Journal Drug Metab. Dispos. Section Abstract Doc Link 16679387 Disease Relevance 0 Pain Relevance 0.32

General Comments

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