INT135591

Context Info Confidence 0.09 First Reported 2006 Last Reported 2006 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 1.27 Pain Relevance 0.48

extracellular space (CSF2, IL8) extracellular region (CSF2, IL8) signal transduction (IL8) intracellular (IL8)

Anatomy Link Frequency T cell 1 CSF2 (Homo sapiens) IL8 (Homo sapiens)

Pain Link Frequency Relevance Heat Inflammation 8 98.32 addiction 1 97.92 cINOD 1 92.00 cytokine 1 78.88 corticosteroid 3 68.68 dexamethasone 2 40.32

Disease Link Frequency Relevance Heat Adhesions 1 99.12 INFLAMMATION 9 98.32 Necrosis 1 81.00 Cancer 1 80.64 Disease 2 70.64 Asthma 3 66.00 Pulmonary Disease 4 64.68

Sentences Mentioned In

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Therefore, we have used adenoviral overexpression to demonstrate NF-kappaB and IKK2 dependence of key inflammatory genes, including intercellular adhesion molecule (ICAM)-1, cyclooxygenase-2, IL-6, IL-8, granulocyte macrophage-colony-stimulating factor (GM-CSF), regulated on activation normal T cell expressed and secreted (RANTES), monocyte chemotactic protein-1 (MCP-1), growth-regulated oncogene-alpha (GROalpha), neutrophil-activating protein-2 (NAP-2), and epithelial neutrophil activating peptide 78 (ENA-78) in primary human airways smooth muscle cells.

GM-CSF Regulation (regulated) of IL-8 in T cell associated with addiction, inflammation and adhesions

1) Confidence 0.09 Published 2006 Journal Mol. Pharmacol. Section Abstract Doc Link 16687566 Disease Relevance 1.27 Pain Relevance 0.48

General Comments

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