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Context Info
Confidence 0.36
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.73
Pain Relevance 1.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein complex (Syp)
Anatomy Link Frequency
cerebral cortex 1
Syp (Rattus norvegicus)
Pain Link Frequency Relevance Heat
amygdala 147 99.68 Very High Very High Very High
Thalamus 2 99.24 Very High Very High Very High
cerebral cortex 1 98.90 Very High Very High Very High
anesthesia 6 97.06 Very High Very High Very High
isoflurane 1 92.12 High High
Versed 1 88.24 High High
Calcitonin gene-related peptide 1 85.04 High High
Spinal cord 1 75.44 Quite High
Peripheral nerve injury 2 75.00 Quite High
Root ganglion neuron 4 68.40 Quite High
Disease Link Frequency Relevance Heat
Anxiety Disorder 76 99.66 Very High Very High Very High
Body Weight 1 89.20 High High
Nervous System Injury 2 75.00 Quite High
Ganglion Cysts 4 68.00 Quite High
Apoptosis 1 57.76 Quite High
Shock 20 5.00 Very Low Very Low Very Low
Overdose 2 5.00 Very Low Very Low Very Low
Aids-related Complex 1 5.00 Very Low Very Low Very Low
Neuropathic Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We found that this general anesthesia causes permanent neuronal deletion in the most vulnerable brain regions-the cerebral cortex and the thalamus-while transiently modulating protein levels of synaptophysin, synaptobrevin, amphiphysin, SNAP-25, and CaM kinase II.
synaptophysin Binding (levels) of in cerebral cortex associated with anesthesia, thalamus and cerebral cortex
1) Confidence 0.36 Published 2007 Journal Ann. N. Y. Acad. Sci. Section Abstract Doc Link 18077565 Disease Relevance 0.15 Pain Relevance 0.53
The distribution of synaptoporin and its relationship with synaptophysin in sensory afferent fibers remain unclear.
synaptophysin Binding (relationship) of
2) Confidence 0.32 Published 2006 Journal Neuroscience Section Abstract Doc Link 16777346 Disease Relevance 0.21 Pain Relevance 0.22
In the present study, we show that auditory Pavlovian fear conditioning is associated with significant and persistent increases in the expression of the postsynaptically-localized protein GluR1 and the presynaptically-localized proteins synapsin and synaptophysin in the LA.
synaptophysin Binding (associated) of associated with anxiety disorder and amygdala
3) Confidence 0.26 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2888610 Disease Relevance 0.37 Pain Relevance 0.34

General Comments

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